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Jay N Cohn Selected Research

Isosorbide Dinitrate (Isordil)

12/2014G-protein beta-3 subunit genotype predicts enhanced benefit of fixed-dose isosorbide dinitrate and hydralazine: results of A-HeFT.
9/2014Effect of fixed-dose combination of isosorbide dinitrate and hydralazine on all hospitalizations and on 30-day readmission rates in patients with heart failure: results from the African-American Heart Failure Trial.
8/2012Effect of fixed-dose combined isosorbide dinitrate/hydralazine in elderly patients in the African-American heart failure trial.
12/2009Relationship of quality of life scores with baseline characteristics and outcomes in the African-American heart failure trial.
11/2008Exploring the potential synergistic action of spironolactone on nitric oxide-enhancing therapy: insights from the African-American Heart Failure Trial.
6/2007Isosorbide dinitrate and hydralazine in a fixed-dose combination produces further regression of left ventricular remodeling in a well-treated black population with heart failure: results from A-HeFT.
4/2007Early and sustained benefit on event-free survival and heart failure hospitalization from fixed-dose combination of isosorbide dinitrate/hydralazine: consistency across subgroups in the African-American Heart Failure Trial.
1/2007Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial.
1/2007Effects of ACE inhibitors or beta-blockers in patients treated with the fixed-dose combination of isosorbide dinitrate/hydralazine in the African-American Heart Failure Trial.
12/2006Outcomes by gender in the African-American Heart Failure Trial.
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Jay N Cohn Research Topics

Disease

79Heart Failure
01/2022 - 04/2002
12Hypertension (High Blood Pressure)
11/2017 - 08/2002
9Cardiovascular Diseases (Cardiovascular Disease)
10/2018 - 06/2004
4Inflammation (Inflammations)
11/2018 - 05/2006
4Myocardial Infarction
11/2017 - 10/2003
3Disease Progression
10/2018 - 01/2006
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2012 - 08/2007
3Sudden Death
10/2009 - 10/2002
3Ventricular Remodeling
06/2007 - 10/2003
3Atrial Fibrillation
06/2006 - 03/2005
2Coronary Disease (Coronary Heart Disease)
01/2021 - 03/2004
2Overweight
01/2021 - 04/2007
2Obesity
01/2021 - 11/2019
2Diabetes Mellitus
01/2018 - 01/2012
2Albuminuria
12/2017 - 08/2007
2Heart Diseases (Heart Disease)
11/2017 - 11/2006
2Myocardial Ischemia (Ischemic Heart Diseases)
01/2016 - 05/2006
2Essential Hypertension
09/2011 - 08/2002
2Proteinuria
10/2009 - 11/2007
2Atherosclerosis
09/2008 - 01/2007
2Prehypertension
08/2007 - 01/2007
1Death (Near-Death Experience)
01/2021
1Carcinogenesis
11/2019
1Fibrosis (Cirrhosis)
11/2018
1Type 2 Diabetes Mellitus (MODY)
01/2018
1Left Ventricular Dysfunction
01/2018
1Stroke (Strokes)
11/2017
1Body Weight (Weight, Body)
04/2015
1ST Elevation Myocardial Infarction
08/2012
1Hypertensive Crisis
09/2011
1Tachycardia (Tachyarrhythmias)
09/2011
1Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced)
09/2011
1Headache (Headaches)
09/2011
1Eclampsia
09/2011
1Chronic Renal Insufficiency
10/2009
1Dyslipidemias (Dyslipidemia)
02/2009
1Systolic Heart Failure
11/2008
1Cardiovascular Abnormalities
07/2008
1Chronic Obstructive Pulmonary Disease (COPD)
12/2007
1Renal Insufficiency (Renal Failure)
12/2006

Drug/Important Bio-Agent (IBA)

34Valsartan (Vals)FDA Link
01/2016 - 09/2002
18Brain Natriuretic Peptide (Natrecor)FDA Link
01/2022 - 11/2002
16Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
11/2013 - 06/2002
12Hydralazine (Apresoline)FDA LinkGeneric
12/2014 - 06/2002
12Isosorbide Dinitrate (Isordil)FDA LinkGeneric
12/2014 - 06/2002
10Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2003
10Angiotensin Receptor AntagonistsIBA
10/2009 - 08/2002
7Troponin T (Troponin T1)IBA
01/2022 - 09/2007
7pro-brain natriuretic peptide (1-76)IBA
01/2022 - 08/2006
5Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2008 - 10/2003
4Neurotransmitter Agents (Neurotransmitter)IBA
06/2006 - 11/2002
4Norepinephrine (Noradrenaline)FDA LinkGeneric
05/2006 - 04/2002
4Pharmaceutical PreparationsIBA
01/2006 - 08/2002
3Trinitrotoluene (TNT)IBA
11/2020 - 02/2019
3Vasodilator Agents (Vasodilators)IBA
10/2009 - 10/2002
3C-Reactive ProteinIBA
04/2007 - 08/2005
3CreatinineIBA
12/2006 - 03/2006
3Hemoglobins (Hemoglobin)IBA
12/2006 - 08/2005
3Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
11/2006 - 10/2002
3PerindoprilFDA LinkGeneric
02/2004 - 01/2004
2TroponinIBA
01/2018 - 01/2012
2Glucose (Dextrose)FDA LinkGeneric
01/2018 - 08/2007
2Retinaldehyde (Retinal)IBA
12/2017 - 08/2007
2Antihypertensive Agents (Antihypertensives)IBA
06/2011 - 02/2004
2ReninIBA
12/2010 - 06/2007
2Digoxin (Digitek)FDA LinkGeneric
09/2010 - 06/2007
2Mineralocorticoid Receptor AntagonistsIBA
11/2008 - 07/2004
2Endothelins (Endothelin)IBA
06/2006 - 07/2004
2AldosteroneIBA
05/2006 - 09/2003
2moxonidine (Moxon)IBA
10/2003 - 04/2002
1ColchicineFDA LinkGeneric
01/2021
1Insulin (Novolin)FDA Link
01/2018
1Biological ProductsIBA
04/2015
1Guanine NucleotidesIBA
12/2014
1GTP-Binding Proteins (G-Protein)IBA
12/2014
1Carrier Proteins (Binding Protein)IBA
12/2014
1Aligeron (AS 2)IBA
05/2014
1Galectin 3 (LGALS3)IBA
05/2013
1LectinsIBA
05/2013
1Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric
09/2011
1Minoxidil (Rogaine)FDA LinkGeneric
09/2011
1Growth Differentiation Factor 15IBA
10/2010
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
04/2009
1Amlodipine (Norvasc)FDA LinkGeneric
02/2009
1Atorvastatin (Lipitor)FDA Link
02/2009
1Spironolactone (Aldactone)FDA LinkGeneric
11/2008
1Telmisartan (Micardis)FDA Link
09/2008
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
08/2007
1LipidsIBA
08/2007
1AngiotensinsIBA
06/2007
1DiureticsIBA
06/2007
1Nitric Oxide Synthase (NO Synthase)IBA
01/2007
1Angiotensin IIIBA
11/2006

Therapy/Procedure

37Therapeutics
10/2018 - 04/2002
3Drug Therapy (Chemotherapy)
12/2017 - 08/2007
3Resuscitation
10/2009 - 10/2002
1Percutaneous Coronary Intervention
11/2017
1Life Support Care
07/2015
1Length of Stay
12/2014
1Critical Care (Surgical Intensive Care)
09/2011